Drostanolone known by its trade name Masteron is an anabolic steroid and belongs to the family of steroids that are derived from Dihydrotestosterone (DHT). Like all anabolic steroid analogues and derivatives, Masteron is a man-made modified version of steroids like Testosterone, Dihydrotestosterone, and Nandrolone, all found in the human body in the natural form.
Masteron has the anabolic rating of 62- 130 and adrogenic rating of 25- 40. These degrees are very low as compared to that of testosterone, which has the strength of 100 for both its anabolic and androgenic properties. All anabolic and DHT derived drugs are compared with the standard measuring bar of Testosterone. This is because it is the original steroid that is naturally present in all our bodies.
Drug for Treating Breast Cancer
Masteron has emerged as one of the most important steroids in the treatment of breast cancer in women by inhibiting and preventing tumors. It has become popular for this purpose as an antineoplastic agent with low anabolic and androgenic strength. It brings down the estrogen levels in the body without the virilizing effects that were seen in women due to the use of other anabolic steroids.
Some patients found the use of Masteron with Tamoxifen (a Selective Estrogen Receptor Modulator) to initially be more helpful than chemotherapy. It has been found that Masteron interacts with certain enzymes in the body to prevent aromatization of other steroids present in the body that reduce estrogen levels. The Food and Drug Administration approved to the production of this steroid for precisely this reason. Historically speaking, it was first brought out in the markets by pharmaceutical companies Lilly and Syntex and some people say that it is one of those few steroids that were made by keeping women in mind.
For Body Builders
Masteron’s importance as medication for cancer has diminished over the years due to various reasons but it is one of the most sought after drugs by body builders. This is because of the same reasons the steroid was so popular for the treatment of breast cancer. It does not aromatize and interact with estrogen already present to get converted into a blocker at the site of reception in the body. It works very well as an ancillary drug to combat estrogenic or progestronic side effects of other steroids that one might be using. It can be included in your steroid cycle instead of Arimidex and Letrozole as a drug to fight side effects.
Although its anabolic and androgenic strengths fall in the mild or low category, its androgenic properties are very visible, including hardening of the muscle and deepening of the voice. Masteron hardens muscles while keeping the fat or lipid content low in the body. Its cycle is short which means it lasts in the body for not more than 60 hours after consumption. This makes Masteron an effective “pre-contest” steroid. Also, its effects have been found to be most pronounced when administered on a body, which already has minimal fat and falls in the category of skinny. On contrary to what was popularly believed, it is not to be used by women other than for treatment. It has been observed over the years that its adrogenic properties are strong despite having a low strength. This is because being a DHT drug; it is five times more adrogenic than testosterone to which it is compared. To top it, it has shown a couple of times more affinity to receptor sites present in the body.
Drostanolone is the name Masteron is known by in the pharmaceutical world. It is a long abbreviation of Dihydrotestosterone or DHT as laymen know it. Chemically, it has a methyl group that is attached to the second carbon atom - 2alpha-methyl-androstan-3-one-17beta-ol or 2alpha-methyl-dihydrotestosterone. It has a molecular weight of 304.46 g/mol. Its formula is C2OH32O2. Masteron is available in two forms – Propionate and Enanthate. They have a half-life of 4.5 days and 10 days respectively and require almost 2 weeks for detection.
Since it is a modified version of DHT, it has a little more anabolic strength than Testosterone. This happens because of the methyl group addition. Due to this Masteron is rendered more resistant to being metabolized by the enzyme 3-hydroxysteroid dehydrogenase. This enzyme creates metabolites called 3-Alpha Androstanediol and 3-Beta Androstanediol, which are inactive in the body and do not serve any anabolic purpose.
The Two Kinds
Out of the two kinds of Masteron that are available, the Propionate version is more popular than the Enanthate version. Propionate here refers to Propoinic acid. Once this acid is attached with Masteron as an ester bond or ester linkage. 17-beta hydroxyl is the parent to which the acid is bound on the Drostanolone chemical structure. Due to the ester presence, the hormone achieves a better half-life and provides extended release of the substance in the body. Once Masteron is released in the body and enters the blood, enzymes rush to break the compound into smaller parts.
In this case, the bond between the ester and the hormone is broken. This breaking requires time which is directly propotional to the length of the ester. The longer the ester, the more time it requires for the enzyme to break it. Eventually, the ester is eliminated from the body, leaving behind pure hormone to do its work uninterruptedly in this case, Masteron.
Addiction of an ester serves no purpose in the body other than increasing the time taken by the enzymes to work on the molecules. Enanthate has a longer ester than Proponiate and hence has a half-life of 10 days.
Results – More Pros than Cons
Masteron being a DHT derivative is incapable of interacting with enzymes in the body to get converted into estrogen. It is safe to use Masteron, even at high doses without the risk of side effects like water retention, high blood pressure, fat gain and gynecomastia. Use of Masteron will lead to only mass gain that is lean and eliminate water weight. For this reason, it is known as a “cutting” drug. It is a very popular anabolic drug among body builders for pre-contest preparation. It chisels the muscles and adds mass to them without water.
Masteron is a mild strength anabolic and androgenic steroid. According to some experienced bodybuilders, Masteron works better when combined with stronger anabolic steroids. Though its strength is more than what it claims on paper, it works the best on a body that is already in a very lean state with a very low fat percentage in the body. This property of the drug is again associated with its ability as an aromatase inhibitor. This is the primary reason for Masteron to function as a water inhibitor as well.
As is the case with all steroids, Masteron reacts differently in each person’s body. The side effects, similarly, vary in existence and degree with each person. Some of the common side effects that have been observed over a period of time are:
It is important to be aware of these possible effects in order to decide the dosage of Masteron in your cycle. But if Masteron works the best for your requirements; there are drugs like Finasteride and Accutane to cope with hair loss and acne respectively.
In comparison to other drugs, there are few positive characteristics to Masteron. It is one of the best steroids for maintaining blood pressure levels in the body. Usually with the ingestion of drugs that create water retention in the body also lead to an elevated blood pressure. Masteron on its own is safe in this regard.
Masteron is also one of those few steroids that are unalkanalyed in the body and do not compromise your liver functioning. It’s a drug that dissolves fast after injecting in the body and can also be used by people who have a history of any drug abuse, hepatitis, liver cancer and other aliments that affect the liver.
How Much is Good Enough
Not many anabolic drugs give a chiseled and hardened look that Masteron is capable of. This is because of its anti-estrogen properties explained earlier. A lot of body builders say that their muscles feel fuller and tighter with the use of Masteron. The drug extracts water from between the muscles and skin, resulting in the visibility of finer muscle details. It is important to remember that this happens only with a body fat percent that is below 10. Masteron on its own is a very weak anabolic steroid and needs to be used with other stringer ones. But it does serve the dual purpose of “cutting” and countering water and estrogen related side effects caused by the use of other drugs.
Masteron can be included in any drug stack that consists of testosterone. There are a few dosage recommendations, but it is ideal to take it under medical supervision and guidance. It is an oil-based substance that has to be injected in the body. For a Proponiate version of Masteron, 300 to 500mg per week, injected alternative days is a good dosage. But, if you are looking for a longer half-life, the Enanthate version of Masteron can be injected twice a week with the dose amount being around 400 to 600mg per week.
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